LymeX Diagnostic Prize

A $10+ million competition to accelerate the development of Lyme disease diagnostics.

Six Phase 3 teams are planning clinical performance studies to validate their novel diagnostics for detecting active Lyme disease infections in people.

About the competition

The goal of the LymeX Diagnostics Prize is to accelerate the development of diagnostics that can accurately detect active Lyme disease infections in people. The multiphase competition is nurturing the development of innovative solutions toward Food and Drug Administration review and clearance. The first two phases of the competition awarded $3 million in prizes, and Phases 3 and 4 will award up to $5.1 million in prizes.

The LymeX Innovation Accelerator (LymeX) was established through a public-private partnership between the U.S. Department of Health and Human Services (HHS) and the Steven & Alexandra Cohen Foundation. The LymeX Diagnostics Prize was launched by this partnership, with the purpose of advancing scientific, technical, and clinical innovation to transform the diagnostics ecosystem for Lyme disease.

The LymeX Diagnostics Prize is made possible through a pledge of more than $10 million from the Steven & Alexandra Cohen Foundation.

LymeX Diagnostics Prize timeline

Phase 1 was open to all eligible entrants to submit concept papers and plans for development. In Phase 2, 10 teams participated in a virtual accelerator to help them refine their concepts. In Phase 3, six teams will plan clinical performance studies toward validating their proposed solutions.

Competition launch

May 17, 2022

Phase 1 winner announcement

November 4, 2022

Phase 2 winner announcement

February 6, 2024
We are here

Phase 3 launch

April 10, 2024

Phase 3 submission deadline

October 31, 2024

Phase 3 winner announcement

December 2024

Phase 4 launch

January 2025

Phase 4 submission deadline

October 2026

Phase 4 winner announcement

December 2026

Prize pool

A judging panel recommended 10 Phase 1 winners according to official evaluation criteria. Phase 1 winners were awarded $100,000 each from the $1 million Phase 1 prize pool and advanced to Phase 2.

A judging panel recommended five Phase 2 winners according to the official evaluation criteria. Phase 2 winners were awarded $265,000 each from the $2 million Phase 2 prize pool. Nine teams were also awarded prizes of $75,000 each based on judges’ evaluations of interim submissions.

A judging panel will recommend up to six Phase 3 winners to receive a share of the $2.1 million Phase 3 prize pool.

$2.1 million

Phase 3 prize pool

Stay informed about the competition.